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Normal controls
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2-kidneys-1-clip model of hypertension
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1-kidney-1-clip model of hypertension
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P
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Heart rate (bpm)
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455.3 ± 60.8
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472.5 ± 54.9
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463.6 ± 55.4
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ns
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Systolic blood pressure - baseline (mmHg)
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100.9 ± 5.5
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144.8 ± 13.0
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152.3 ± 16.6
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<0.0001
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Diastolic blood pressure - baseline (mmHg)
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76.7 ± 4.3
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106.4 ± 12.7
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109.2 ± 8.7
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0.0001
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Heart rate – after atropine (bpm)
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559.8 ± 58.1
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575.9 ± 82.5
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604.4 ± 55.4
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ns
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Systolic blood pressure - after atropine (mmHg)
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108.9 ± 6.6
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152.7 ± 16.1
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151.2 ± 15.3
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<0.0001
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Diastolic blood pressure - after atropine (mmHg)
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85.9 ± 6.0
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116.0 ± 11.9
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111.2 ± 8.4
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<0.0001
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Heart rate – after metoprolol (bpm)
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463.0 ± 74.0
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513.8 ± 67.6
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479.3 ± 49.4
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ns
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Systolic blood pressure - after metoprolol (mmHg)
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100.2 ± 10.8
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155.1 ± 14.9
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151.1 ± 15.3
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<0.0001
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Diastolic blood pressure - after metoprolol (mmHg)
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77.3 ± 9.2
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114.1 ± 13.4
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111.4 ± 10.5
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<0.0001
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- Statistical analysis was performed among groups.
